Abstract

Two simple and convenient simultaneous spectrophotometric methods for determination of ethinylestradiol and levonorgestrel in a combination dosage form were developed. These are based on native maxima of ethinylestradiol and levonorgestrel at 281 and 244 nm respectively when chloroform was used as a solvent. Both the drugs obey Beer's law in the concentration range employed for these methods. The results of analysis have been validated statistically and by recovery studies.