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Abstract

Ssynthesis of 1-alpha-aryloxypropionyl-3-methyl-5-pyrazolones and related compounds as possible antifungal agents.

Author(s): SK Srivastava, RB Pathak, SC Bahel
Chemistry Dept., Gorakhpur University, Gorakhpur-273009,

Correspondence Address:
S K Srivastava Chemistry Dept., Gorakhpur University, Gorakhpur-273009

Some new 1-alpha-aryloxypropionyl-3-methyl-5-pyrazolones (la-c) have been prepared. These on condensation with aromatic aldhydes yielded mono arylidene derivatives (LLa-i). All these compounds have been evaluated for their antifungal activity against A. niger and H. oryzae. Based on the screening data, a possible structure activity relationship has been discussed.

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