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Abstract

Study of the Effectiveness of Renshen Yangrong Decoction in Combination with Conventional Drugs in the Treatment of Dilated Cardiomyopathy

Author(s): Xiangyu. Meng, Yue Du, Chengjie Song and Zhilin Cui*
Department of Traditional Chinese Medicine, The First Clinical Medical College of Heilongjiang University of Traditional Chinese Medicine, Haerbin 150500, 1Heilongjiang University of Traditional Chinese Medicine School of Basic Medicine, Haerbin 150081, 2Preventive Treatment Center, Daqing Traditional Chinese Medicine Hospital, Daqing 163311, China

Correspondence Address:
Zhilin Cui, Heilongjiang University of Traditional Chinese Medicine School of Basic Medicine, Haerbin 150081, China, E-mail: tongqingtang678@163.com


To investigate the effect of Renshen Yangrong decoction combined with conventional drugs in the treatment of dilated cardiomyopathy. 107 patients with dilated cardiomyopathy were divided into a Chinese medicine group (n=54) and a control group (n=53) using the random number table method. Control group received placebo combined with conventional medication and Chinese medicine group received Renshen Yangrong decoction combined with conventional medication. The clinical efficacy, cardiac function indexes, serological indexes, quality of life scores and adverse effects of the two groups were compared. The overall treatment efficiency of Chinese medicine group was higher than that of control group (p<0.05). After treatment, Chinese medicine group had higher left ventricular ejection fraction, blood volume, serum N-terminal pro-B-type natriuretic peptide, serum procollagen type I carboxy-terminal peptide, serum procollagen type III carboxy-terminal peptide and all Minnesota heart failure quality of life scale scores than control group (p<0.05) and the left ventricular end-diastolic diameter was lower than control group (p<0.05). No adverse events occurred in either group. Renshen Yangrong decoction combined with conventional drugs is safe and effective in the tr eatment of dilated cardiomyopathy.

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