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Abstract

Synthesis And Antitubercular Activity Studies Of Substituted 2-Pyrazolines

Author(s): P Manoj Kumar, R Ajay Kumar, T. K Ravi

Certain substituted 2-pyrazolines were synthesized by reaction between isoniazid and chalcones of type A(1-9). All compounds were tested for antitubercular activity against M. tuberculosis H37Rv) strain by using alamar blue assay. Of all the pyrazoline compounds tested, compounds P1, P4, P5, P7 and P9 showed good antimycobacterial activity comparable to standard drug lsoniazid.

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