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Abstract

Synthesis And Biological Activity Of 2-(3', 5', -Dibromo-2'-Hydroxypheny)-3-Aryl-5H/Methyl/Carboxymethyl-4-Thiazolidinones

Author(s): A. H Bapodra, Fatema Bharmal, Hansa Parekh

With a view to map out the synthesis and antimicrobial activity of series of 2-(3',5'-dibromo-2'- hydroxyphenyI)-3-aryl-5H/methyl/carboxymethyl-4-thiazolidinones (Ill-a-ss) have been prepared by the cyclocondensation of N-substituted-(3,5-dibromo-2-hydroxy benzylidene)-anilines (ll) with a-substituted mercaptoacetic acids and evaluated for their in vitro growth inhibiting activity against several microbes. Some of the compounds show significant antimicrobial activity.

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