All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Synthesis and invitro amoebicidal activity of some n,n'-disubstituted diamine dihydrochlorides.

Author(s): PL Kachroo, R Gupta, R Wadhwan
DEpt. of Chemistry, University, of Jammu, Jammu-180 001,

Correspondence Address:
P L Kachroo

Sixteen N'-alkyl and N'-aryl-N-[3-(2, 4-dialkoxy-5-alkylphenyl) propyl]-1, 2- diaminoethanes (IV) have been synthesised by treatment of 2,4-dialkoxy-5-alkylbenzene-propanoylchlorides with glycine followed by conversion of the resultant acids (III) into acid chlorides; condensation of acid chlorides with amines and LAH reduction of resultant diamides. The diamines isolated as dihydrochlorides have been tested in vitro for amoebicidal activity against E. histolytica.

PDF

 
 
Google scholar citation report
Citations : 69022

Indian Journal of Pharmaceutical Sciences received 69022 citations as per google scholar report