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Synthesis And Pharmacological Activity Of 4-Aryl-Thieno-(2,3-d)-Pyridazines

Author(s): A. K Singh, G. L Hegde, S. A Khanum, S Shashikanth

A facile synthesis of 4-aryl-thieno-[2,3-d]-pyridazines (4a-g) have been achieved by cyclisation of 1-aroylhydrazones (3a-g) using polyphosphate ester. All the synthesized compounds have been characterized by elemental analysis and spectral data. In addition, they were screened for antibacterial, antifungal, anticonvulsant and antiinflammatory activities.


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