All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


Synthesis of new 1, 3, 4-oxadiazolo [3, 2-a]-s-triazine-5, 7-dithiones and the - dithionone analogues as potential antifungal agents.

Author(s): H Singh, L DS Yadav, KN Shukla, R Dwivedi
Dept. of Chemistry, University of Gorakhpur, Gorakhpur-273 009,

Correspondence Address:
H Singh Dept. of Chemistry, University of Gorakhpur, Gorakhpur-273 009

N1-Aryl-N3-(5-aryl-1, 3, 4-oxadiazol-2-yl) thioureas (II a-d) on cyclocondensation with CS2/KOH and ethyl chloroformate afford 2, 6-diaryl-1, 3, 4-oxadiazolo [3, 2-a]-s-triazine-5, 7-dithiones (III a-d) and their - thionones analogues (IV a-d) respectively. 2, 6-Diaryl-5-thioxo-1, 3, 4-oxadiazolo [3, 2-a]-s-triazin-7-ones (VI a-d) are obtained by trating oxadiazolycarbamates (V a-b), the condensation products of 1, 3, 4-oxadiazoles and ethyl chloroformate, with aryl isothiocyanates. The compounds II to VI have been screened for their antifungal activity against A. flavus and F. solani.


List of Supporting Conferences