All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


Synthesis of new 5-substituted-4-phenyl-3-aryloxymethyl/phenylethyl 1,2,4-triazoles and their antimicrobial activity

Author(s): RH Khan, R AK Srivastava, RC Rastogi
Regional Research Laboratory, Jorhat 785 006, Assam

Correspondence Address:
R H Khan Regional Research Laboratory, Jorhat 785 006, Assam

Some hydrazides (III), amides (IV, V) have been synthesised by the reaction of 3,4-disubstituted ethyl 1,2,4-triazole-5-meracaptoacetates (I) with hydrazines and cyclic secondary amines respectively. The hydrazides obtained were treated with phenyl isothiocynate to afford the triazolomethylmercaptotriazoles (IV), while with aldehyde, arylidene derivatives (VII-X) were obtained. These compounds have been tested for their antibacterial and antifungal activity. Only compounds IIa, IIb, VIa-c, Xa and Xc exhibit the activity of high order.


List of Supporting Conferences