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Abstract
The antibacterial properties of the liquid antiseptic tcp.
Author(s): YB Acheampong, A El-Mahmood, PF Olurinola
Dept. of Pharmaceutics and Pharmaceutical Microbiology, Ahmadu Bello University, Zaria Nigeria,
Correspondence Address:
Y B Acheampong Dept. of Pharmaceutics and Pharmaceutical Microbiology, Ahmadu Bello University, Zaria Nigeria
Dept. of Pharmaceutics and Pharmaceutical Microbiology, Ahmadu Bello University, Zaria Nigeria,
Correspondence Address:
Y B Acheampong Dept. of Pharmaceutics and Pharmaceutical Microbiology, Ahmadu Bello University, Zaria Nigeria
The antibacterial properties of the liquid antiseptic TCP against Staphylococcus aureus and Pseudomonas aeruginosa were essentially similar. The activity of the antiseptic was 4-8 times that of equivalent concentration of pure phenol. Use-dilutions of the antiseptic had lethal effect and exhibited the logarithmic order of death. The MIC and MBC of the antiseptic increased in tap water to values similar to those obtained in the presence of serum. Tap water also adversely affected the death rates of the use-dilutions by about 50 percent. The usefulness of the product and the implication of the adverse effect of tap water on the activity are discussed.
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