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Abstract

The Application of Enoxaparin Sodium Injection in the Treatment of Cerebral Infarction

Author(s): N. Wang* and X. Liu
9th division, The 5th People's Hospital of Ji'nan, 24297 Jingshi Road, Huaiyin District, Jinan, 250022, Shandong Province, China

Correspondence Address:
9th division, The 5th People's Hospital of Ji'nan, 24297 Jingshi Road, Huaiyin District, Jinan, 250022, Shandong Province, China, E-mail: [email protected]

The clinical efficacy of enoxaparin sodium injection on cerebral infarction was explored and the mechanism of action of enoxaparin sodium was analyzed, which provided certain basis for the clinical antithrombotic treatment of acute cerebral infarction. A total of 68 patients with acute cerebral infarction treated in the 5th People's Hospital of Ji'nan from January 2016 to January 2019 were selected as the research subjects and were divided into the observation group and the control group through the random number table method, with 34 patients in each group. After being admitted to the hospital, patients in both groups were treated with routine treatments and nursing interventions by the Neurology Department; in addition, patients in the control group were given oral aspirin, and patients in the observation group were given oral aspirin and enoxaparin sodium injection. After being treated for 14 days, the clinical efficacy, European Stroke Scale results, and National Institutes of Health Stroke Scale results of patients in both groups were compared; in addition, the side effects of patients in both groups during the treatment courses were observed and recorded. The research results showed that the overall treatment effective rate in the observation group was 94.12 %, which was significantly (p<0.05) higher than the 70.59 % effective rate in the control group. The European Stroke Scale and National Institutes of Health Stroke Scale results of patients in both groups were improved after the treatment and the differences between the observation and the control group were statistically significant (p<0.05). In summary, the therapeutic effects of enoxaparin sodium injection in combination with aspirin were positive and such treatment plans could effectively improve the neurological deficiency without increasing the risks of hemorrhage, which was worth being widely applied clinically. However, the deficiencies of the research process, such as a small sample size and incomplete observation indicators, required improvement in subsequent research.

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