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Abstract

The Clinical Effect of Domperidone on Reflux Gastritis

Author(s): Xiaodan Sui, Houbo Deng, Xuezhu Jin and Yan Leng*
Department of Liver, Spleen and Stomach, Affiliated Hospital of Changchun University of Traditional Chinese Medicine, Changchun 130021, China

Correspondence Address:
Department of Liver, Spleen and Stomach, Affiliated Hospital of Changchun University of Traditional Chinese Medicine, Changchun 130021, China, E-mail: [email protected]

The present clinical study observed the effect of domperidone on reflux gastritis. In this study, 200 patients with reflux gastritis were divided into the control group accepting routine drug therapy and the research group accepting domperidone treatment, each group contained 100 patients. The overall treatment efficiency, clinical symptom score before and after treatment and bile reflux monitoring indicators 24 h after treatment were compared between the two groups. On comparing the overall treatment efficiency of patients in both groups, the results showed that the research group was 96.00 % and the control group was 80.00 %. The score of clinical symptoms of the two groups of patients showed that the degree of improvement in the research group was significantly better than that in the control group after treatment, p<0.05. By comparing the monitoring indexes of bile reflux 24 h after treatment between the two groups, the research group had significant advantages in terms of the percent total reflux time, the number of refluxes and the number of refluxes lasting for more than 5 min. The application of domperidone in the treatment of reflux gastritis can significantly improve the therapeutic effect, improve the clinical symptoms and promote the recovery of patients as soon as possible.

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