Abstract

The objective of present study was to evaluate the effect of bicyclol on liver function impairment induced by antithyroid drugs. One hundred and eighty hyperthyroidism patients treated at the Beijing An Zhen Hospital for liver function impairment induced by antithyroid drugs from June 2015 to October 2018 were enrolled. The patients were divided into the research group receiving bicyclol and the control group receiving tiopronin. The therapeutic efficacy in the both groups was observed and the ultrasound results were recorded. The improvement in the levels of indicators such as aspartate aminotransferase, alanine aminotransferase and total bilirubin was significantly greater in the research group. The incidence of adverse reactions was also significantly lower in the research group. Moreover, the research group showed higher quality of life. In addition, ultrasound showed that treatment with bicyclol could arrest liver function impairment induced by antithyroid drugs. In conclusion, bicyclol could treat the liver function impairment induced by antithyroid drugs.