Abstract

Author(s): Gita Chaurasia, D Bhadra, S Bhadra, N. K Jain

Two simple, fast, convenient, precise, reproducible UV spectrophotometric methods have been developed for the determination of carvedilol in pure form in tablets using methanol (method A) and polyethylene glycol-400: water (2:1) (method B). The UV spectrum of carvedilol showed absorption maxima at 242 nm and 245 nm, respectively in methanol and PEG-400:water (2:1). Good agreement with Beer's law was found in the range of 2 to 20 μg/ml for method A and 1 to 10 μg/ml for method B.

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