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Abstract

Synthesis and biological evaluation of delavayin-C

Author(s): Nirmala V Shinde, M Himaja, SK Bhosale, MV Ramana, DM Sakarkar
Department of Pharmaceutical Chemistry, N. G. S. M. Institute of Pharmaceutical Sciences, Nanthoor, Mangalore-575 005, India

Correspondence Address:
Nirmala V Shinde Department of Pharmaceutical Chemistry, N. G. S. M. Institute of Pharmaceutical Sciences, Nanthoor, Mangalore-575 005 India E-mail: [email protected]


The synthesis of a cyclic heptapeptide, delavayin-C, cyclo(gly-tyr-tyr-tyr-pro-val-pro) is described. The structure of this compound was established on the basis of analytical IR, 1 H NMR and FAB mass spectral data. The antibacterial and antifungal activities of this peptide are also described.



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