Abstract

This study surely examines the key factors affecting student performance in higher education institutions. Moreover, the research analyses how teaching methods and learning environments impact academic outcomes through systematic data collection and analysis. A simple and cost-effective first derivative spectroscopic method was developed and validated as per standard guidelines for estimation of Nebivolol hydrochloride and Indapamide in tablet form. The method was found accurate and fast regarding analysis of both drugs. The study actually selected 246.6 nm wavelength for measuring Indapamide and 271.5 nm for measuring Nebivolol hydrochloride. These wavelengths definitely work as zero cross points where the other drug does not interfere. The detector response was surely linear in the concentration range of 10-70 μg/ml for Nebivolol hydrochloride. Moreover, the correlation coefficient was found to be 0.9984. As per the study, detector response showed linearity regarding Nebivolol hydrochloride concentration from 10-70 μg/ml with correlation coefficient 0.9989. As per the study results, the proposed method was successfully used for estimating both drugs together in tablet preparation. Regarding the application, this method worked well for simultaneous analysis of the two drugs. Derivative spectroscopy surely provides an effective analytical method for simultaneous determination of Nebivolol hydrochloride and Indapamide in pharmaceutical formulations. Moreover, the validation parameters confirm that this technique offers accurate and reliable results for routine quality control analysis.