A HPTLC method for quantitative estimation of swetiamarin in marketed polyherbal antidiabetic formulations

PM Patel1; KN Patel2; NM Patel1; RK Goyal3

doi:10.4103/0250-474X.34560

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Abstract

A HPTLC method for quantitative estimation of swetiamarin in marketed polyherbal antidiabetic formulations

Author(s): PM Patel¹, KN Patel², NM Patel¹, RK Goyal³
¹ Shri B. M. Shah College of Pharmaceutical Education and Research, Modasa - 383 315, India ² Department of Pharmacognosy, L. M. College of Pharmacy, Navrangpura, Ahmedabad - 380 009, India ³ Department of Pharmacology, L. M. College of Pharmacy, Navrangpura, Ahmedabad - 380 009, India

Correspondence Address:
R K Goyal Department of Pharmacology, L. M. College of Pharmacy, Navrangpura, Ahmedabad - 380 009 India E-mail: goyalrk@hotmail.com

DOI: 10.4103/0250-474X.34560

Swetiamarin is one of the phytoconstituents present in Enicostemma littorale Linn. Enicostemma littorale is known for its hypoglycemic activity from ancient times. In the present study an attempt has been made to develop a HPTLC method for quantitative estimation of swetiamarin in plants and different marketed antidiabetic polyherbal formulations. This HPTLC method was found to be reproducible, accurate and precise and could detect swetiamarin concentration at nanogram level. The developed HPTLC method would be an important tool in the way of acceptability of quality control method of polyherbal formulations.

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