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Abstract

A Review on Carbon Nanotubes: As a Nano carrier Drug Delivery System

Author(s): S. PALIWAL*, K. PANDEY, S. PAWAR, H. JOSHI AND N. BISHT
College of Pharmacy, Graphic Era Hill University, Bhimtal Campus, Sattal Road Nainital-263156, Uttarakhand, India

Correspondence Address:
College of Pharmacy, Graphic Era Hill University, Bhimtal Campus, Sattal Road Nainital-263156, Uttarakhand, India, E-Mail: [email protected]


Carbon nanotubes were discovered in 1991, Sumio Iijima gives the theory of carbon nanotubes which is made up of carbon allotrope graphene having brilliant electrical, mechanical, optical and synthetic properties, pulling in extensive enthusiasm for their application in different fields including drug conveyance and malignancy treatment. Malignancy is one of the most testing sicknesses of present day times since its treatment includes recognizing ordinary sound cells from influenced cells. Here, carbon nanotubes assume a significant job since marvels, for example, electronic paramagnetic resonance, permit carbon nanotubes to recognize typical cells from influenced ones, the Holy Grail in malignancy treatment. Significant work has been done on carbon nanotubes as medication conveyance frameworks throughout the most recent 20 y. Not with standing, worries over specific issues, for example, biocompatibility and poisonousness have been raised and warrant broad exploration in this field. For the preparation of Single-walled carbon nanotubes and Multi-walled carbon nanotubes arc discharge, laser ablation and chemical vapor deposition method of preparation are used. By the process of acid treatment, magnetic purification and size exclusion chromatography carbon nanotubes impurities are removed out. Because of hydrophobic nature of carbon nanotubes, Covalent and non-covalent functionalization are done for the surface modification. Cytotoxic of carbon nanotubes have a beneficial effect in cancer treatment. Drug released from carbon nanotubes by using various stimulants such as electric, magnetic field and changes in pH.

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