Abstract

A total of 110 patients with obstructive sleep apnea hypoventilation syndrome were selected from January 2017 to December 2018, including 76 cases of men and 34 females, aged 40-50 y and according to the apnea hyponea index, patients were classified into 3 groups of moderate to moderate and 5 apnea hyponea index 20 was divided into group A (36 cases), the 40 of 20 to apnea hyponea index is divided into group B (45 cases) and apnea hyponea index the 40 of 20 to 40 is divided into group B (45 cases) and apnea hyponea index to 40 is divided into group C (29 cases). In the same period in the health check-up center to extract 40 cases without obstructive sleep apnea hypopnea syndrome, arrhythmia and other medical history of health check-up objects. 24 h Holter-monitoring and polysomography monitoring of 4 groups of people, observed and recorded heart rate variability indicators for each group, including all standard deviations for sinus cardiac arrest, standard deviation per 5 min sinus cardiac interstitial period, the average root mean square of successive differences of the total sinus intercardial period difference is divided by the number of individuals of the sinus cardiac interstitial period of 50 ms the average root mean square of successive differences of the total sinus intercardial period difference is divided by the number of individuals of the sinus cardiac inner struggle period of 50 ms divided by the percentage of the total sinus cardiac inner struggle period (proportion of NN50), low frequency and high frequency. Standard deviation of all sinus beats, standard deviation of the mean value of sinus, root mean square of successive differences, proportion of NN50, low frequency and high frequency were lower than those in the control group (p<0.05) in patients with obstructive sleep apnea hypopnea syndrome. The proportion of NN50 and high frequency in group C were lower than A and B (p<0.05) and the low frequency was higher than the proportion of NN50 and high frequency in group C were lower than A and B (p<0.05) and the low frequency was higher than group A, group B and control group (p<0.05). Holter-monitoring is a non-invasive test, the price is not high and it can be a regular test for testing the autonomic nervous function in patients with obstructive sleep apnea hypopnea syndrome.