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Abstract

Antifatigue Ability of Tea Polyphenols in Exercising Rats after Intragastric Administration

Author(s): D. Liu, Xiao Han1, Y. Cao and H. Wang2*
Daqing Normal University, 1Bupt Department of Physical Education,Bei Jing,100876, 2Harbin Medical University (Daqing), Daqing, China

Correspondence Address:
Daqing Normal University, 1Harbin Medical University (Daqing), Daqing, China, E-mail: [email protected]

In order to explore the antifatigue effect of different doses of tea polyphenols on exercising rats, male Sprague Dawley rats were divided into 5 groups and each group was subjected to different treatments. The antifatigue effect of tea polyphenols on rats was evaluated by analyzing changes in body weight, exhaustion time and levels of internal factors in each group. The results showed that tea polyphenols can reduce the body weight of rats. In the analysis of exhaustive exercise time of rats, it was found that the time to exhaustion in low-dose tea polyphenols group was less than that of middle-dose tea polyphenols group, which is in turn less than that of high-dose tea polyphenols group. Therefore, tea polyphenols appear to effectively improve the endurance of rats antifatigue effect. In the analysis of serum creatine kinase, lactic acid, lactate dehydrogenase and blood urea nitrogen levels in rats of each group, it was found that the levels of creatine kinase, lactic acid, lactate dehydrogenase and blood urea nitrogen levels in rats increase significantly after exhaustion, but the levels of factors in rats decrease after intragastric administration of tea polyphenols. Moreover, the higher the dose of tea polyphenols was, the lower were the levels of creatine kinase, lactic acid, lactate dehydrogenase and blood urea nitrogen levels in rats, which was close to the blank control group. When the levels of IL-1β, TNF-α and IL-10 in serum of rats were analyzed, it was found that after exhaustion, the levels of IL-1β were not significantly increased, while the levels of TNF-α and IL-10 were significantly increased. After intragastric administration of tea polyphenols in rats, TNF-α factor decreased with increasing doses, but the effect on IL-10 was not obvious. Therefore, through this study, it was found that after exercise, rats can be given a certain dose of tea polyphenols to reduce their fatigue and improve ability to recovery. Although there are some shortcomings in the research process, it still provides a reliable basis for the study of the impact of fatigue resistance after exercise.

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