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Antimicrobial screening of some newly synthesised transition metal complexes of a dithiocarbazate derived from isoniazid

Author(s): Shashi B Kalia1, V Sharma2, Kamakshi Lumba1, Geetanjli Kaushal1, Anuradha Sharma2
1 Department of Chemistry, Himachal Pradesh University, Shimla - 171 005, India 2 Department of Microbiology, Indira Gandhi Medical College and Hospital, Shimla - 171 005, India

Correspondence Address:
Shashi B Kalia Department of Chemistry, Himachal Pradesh University, Shimla - 171 005 India E-mail: [email protected]

Some new metal (II) isonicotinoyldithiocarbazates of the general formula [M(IN-DtczH) 2 ]Cl 2 (M = Mn, Co, Ni, Zn; IN-DtczH = isonicotinoyldithiocarbazic acid) and Mn(IN-Dtcz) 2 , having sulphur-nitrogen linkage were synthesized. All the compounds were screened for their antimicrobial activity against the pathogenic bacteria Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcus sp . and the pathogenic fungus Candida albicans by agar dilution method. All the compounds showed good antimicrobial activity.

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