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Abstract

Biosynthesis of Iron Nanoparticles from Pleurotus florida and its Antimicrobial Activity against Selected Human Pathogens

Author(s): M. GURUSAMY1* AND R. RAJU
Department of Biology, The Gandhigram Rural Institute Dindigul, Tamil Nadu- 624001, 1Department of Botany, Sri Kaliswari College, Sivakasi, Tamil Nadu- 626123, India

Correspondence Address:
Department of Botany, Sri Kaliswari College, Sivakasi, Tamil Nadu- 626123, India; E-mail: [email protected]


In the present investigation, iron nanoparticles were synthesized by using mushroom extract. The production of iron nanoparticles from P. florida was initially confirmed by color changes from brown to dark brown within 30 min at 60° and further characterized by Ultraviolet-Visible spectroscopy and scanning electron microscope with Edax. The biosynthesized iron nanoparticles were subjected to antimicrobial activities and showed higher zone of inhibition against Candida glabrata followed by Micrococcus mucilaginosus, Pseudomonas aeruginosa, Candida albicans, Klebsiella terrigena, K. pneumoniae, Escherichia coli, Candida sp., Bacillus cereus and Staphylococcus aureus. This extract was confirmed as effective against microorganisms which was well comparable with standard antibiotics. The present study has recommended that iron nanoparticles from mushrooms have great potential to act as safe alternative to antibiotics to fight the challenges of drug discovery.

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