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Abstract

Clinical Effect Analysis of Compound Cerebral Peptide Injection in the Treatment of Senile Dementia based on Meta-analysis of Medical Database

Author(s): J. Chen, Z. Jiang, Q. Wang and J. Chen*
Department of Neurology, The First Hospital of Lanzhou University, Lanzhou City, 730000, Gansu Province, China

Correspondence Address:
Department of Neurology, The First Hospital of Lanzhou University, Lanzhou City, 730000, Gansu Province, China, E-mail: [email protected]

In order to study the therapeutic effect and safety of compound cerebral peptide injection in the treatment of Alzheimer’s disease, meta-analysis method based on medical database was adopted to comprehensively evaluate the clinical efficacy of compound cerebral peptide injection in the treatment of senile dementia. Firstly, keywords were searched in the medical database for the included studies, and the inclusion criteria and screening conditions were set. Then, the quality of the included studies was evaluated. Finally, meta-analysis, publication bias and sensitivity analysis were carried out for the included studies. In this study, two enrolled studies and 120 patients were screened. The results of meta-analysis showed that the treatment effect of compound cerebral peptide injection group was significantly improved compared with placebo treatment, and the adverse reaction time of compound cerebral peptide injection group was less than that of placebo treatment. Therefore, in the study, it has certain guiding significance for the research on the treatment of Alzheimer’s disease in the aspect of statistics.

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