Abstract
Convalescent Plasma Therapy: A Treatment of Choice for COVID-19 during Current Pandemic
Department of Mechanical Engineering, College of Engineering, 1Department of Periodontics and Community Dental Sciences, College of Dentistry, King Khalid University, Abha 61421, 2Department of Pharmaceutics, College of Pharmacy, King Khalid University, Guraiger, Abha 62529, 3Department of Restorative Dentistry, College of Dentistry, 4Department of Orthodontics, 5Department of Oral Surgery, College of Dentistry, King Khalid University, Abha 61421, Kingdom of Saudi Arabia, 6Department of Periodontology and Implantology, Dr. Harvansh Singh Judge Institute of Dental Sciences, Chandigarh 160014, 7Department of Conservative Dentistry and Endodontics, Jan Nayak Choudhary Devi Dental College, Sirsa, Haryana 125055, India
Correspondence Address:
T. M. Yunus Khan*, Department of Mechanical Engineering, College of Engineering, King Khalid University, Abha 61421, Kingdom of Saudi Arabia, E-mail: yunus.tatagar@gmail.com
The severe acute respiratory syndrome coronavirus 2 which is the source of pandemic coronavirus disease 2019 has engulfed almost whole world. This virus was first reported in Wuhan city (China) in December 2019. Since the discovery of the virus, till today the researchers and scientists have been working to develop new vaccines or therapeutic agents against severe acute respiratory syndrome coronavirus 2. However, thus far no vaccine has emerged that can be approved to treat or prevent coronavirus disease 2019. Due to lack of specific preventative and therapeutic options for the treatment of coronavirus disease 2019, the use of convalescent plasma therapy may be of great benefit in the current situation. Previous use of immune plasma has resulted in successful treatment of hemagglutinin type 1 and neuraminidase type 1 influenza virus, Middle East respiratory syndrome coronavirus and severe acute respiratory syndrome coronavirus 1 epidemics. In the current scenario raised by coronavirus disease 2019, the convalescent plasma therapy has been applied successfully among many patients across various regions. This article presents an up-to-date review of existing literature on recovery through convalescent plasma as a treatment of choice, safety and its efficacy, possibility and its challenges for the treatment of coronavirus disease 2019.
