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Abstract

Effects of Different Anesthesia Methods on NTI Index, Mean Arterial Pressure, Heart Rate and S-100beta Protein in Elderly Patients Undergoing Abdominal Surgery

Author(s): X. Xia, T. Guo, L. Wang, Z. Yang, Z. Zhu and D. Zhang1*
Department of Anesthesiology, The First People's Hospital of Tonglu County, Hangzhou City, 311500, Zhejiang Province, 1Department of Anesthesiology, The People's Hospital of Tongchuan City, Tongchuan City 727000, Shaanxi province, China

Correspondence Address:
Department of Anesthesiology, The People's Hospital of Tongchuan City, Tongchuan City 727000, Shaanxi province, China, E-mail: [email protected]

In order to study the effects of different anesthesia methods on nearest taxon index, mean arterial pressure, heart rate, S-100β protein and other indicators in elderly patients undergoing abdominal surgery, 127 elderly patients hospitalized for abdominal surgery were selected as the study subjects. According to the degree of anesthesia, they were divided into 2 groups one received deep anesthesia and the other shallow anesthesia. The above mentioned indicators were observed in both groups of patients after surgery, to explore the influence of different anesthesia methods on elderly patients. There was no statistical difference in basic information between the two groups, while there was statistical difference in nearest taxon index, mean arterial pressure and heart rate between the two groups (p<0.05). Comparing and analyzing postoperative cognitive dysfunction, postoperative delirium, mini-mental state examination and clock-drawing tests between the two groups, it was found that there was no statistical difference in the comparison of mini mental state exam and CDT scales alone, but the comprehensive comparison between them was more objective and comprehensive, namely post-operative cognitive dysfunction, with statistical difference (p>0.05). In the analysis of serum S-100β protein in two groups, it was found that deep anesthesia not only prevented the increase of S-100β protein, but also quickly restored to the initial level. Therefore, through this study, it is found that different depths of anesthesia has no significant effect on the cognitive function of the elderly, but deep anesthesia has a lower incidence of post-operative cognitive dysfunction than shallow anesthesia and can effectively reduce the level of S-100β protein in patients.

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