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Hepatoprotective Effect of Indigenous Medicinal Plants-A Review

Author(s): M. Minnady, G. Jayapal, Sasikala Poochi, P. Nethaji and B. Mathalaimuthu*
Department of Zoology, Annamalai University, Annamalai nagar, Tamil Nadu 608002, 1Department of Zoology, Poompuhar College (Autonomous), Melaiyur 609107, 2Department of Chemistry, Annamalai University, Annamalai nagar, Tamil Nadu 608002, India

Correspondence Address:
B. Mathalaimuthu, Department of Zoology, Annamalai University, Annamalai nagar, Tamil Nadu 608002, India, E-mail:

Liver is an important part in human beings and plays a very important and major role in metabolism and excretion of xenobiotics from the body. Further, hepatotoxicity is caused by different types of toxic chemicals, such as antibiotics and chemotherapeutic agents, paracetamol (C8H9NO2), thioacetamide (C2H5NS), carbon tetrachloride (CCl4), silymarin (C25H22O10), ethanol (C2H5OH) and excessive alcohol intake and microbes is well researched. The markedly available synthetic drugs to treat liver sickness in this condition also cause further damage to the liver. Therefore, herbal medicines have become increasingly famous and their utilization is wide-spread. In medicinal plant derived drugs have been utilized in the treatment of liver diseases for a long time the protection of a healthy liver has been essential for the overall well-being of an individual. Liver injury induced by toxins is more common now-a-days. Herbal remedies are focused in the pharmaceutical industry to evolve a safe route for liver disorders and it is very low cost, no side effects compare with synthetic drugs. Therefore, hepatoprotective plants such as Avicennia alba, Anisochilus carnosus, Baliospermum montanum, Centella asiatica, Clitoria ternatea, Eclipta alba, Justicia adhatada, Phyllanthus emblica, Pisonia Grandis and Syzgium cuminiare were reviewed. The present review is aimed at compiling data on promising phytochemicals from medicinal plants that have tested in hepatotoxicity models using modern scientific system.

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Citations : 66710

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