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Improvement of Vitamin A and Trace Elements in Children with Anemia

Author(s): T. DING* AND Q. JIANG
Department of Pediatric, Zhejiang Xiaoshan Hospital, No. 728 Yucai Road (north), Xiaoshan, Hangzhou, 311202, China

Correspondence Address:
Department of Pediatric, Zhejiang Xiaoshan Hospital, No. 728 Yucai Road (north), Xiaoshan, Hangzhou, 311202, China, E-mail:

In order to study the improvement of vitamin A and trace elements in children with anemia, children whose serum vitamin A is lower than 0.7 μmol/l or hemoglobin is lower than 115 g/l were selected as research subjects and were divided into the iron supplementation group, the vitamin A supplementation group and the control group (only nutrition education). Serum vitamin A was determined using high performance liquid chromatography. Hemoglobin was measured by semi-automatic hematology analyzer. Serum ferritin and serum transferrin receptor were measured using enzyme-linked immunosorbent assay. Serum vitamin A, hemoglobin, serum ferritin, serum transferrin receptor, prevalence of vitamin A deficiency and anemic changes were compared and analyzed before and after the treatment. The results showed that the serum vitamin A, hemoglobin and serum transferrin receptor levels in the group supplemented with vitamin A were significantly higher than those recorded prior to starting treatment. The level of serum ferritin, vitamin A deficiency and anemia were significantly lower after the treatment. The levels of hemoglobin and serum transferrin receptors in the group supplemented with iron were significantly higher after the treatment while serum ferritin level, vitamin A deficiency decreased significantly after the treatment. Although the level of vitamin A in serum increased but this increase was not significant, while the levels of all these indicators in the control group remain unchanged after treatment.

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