Interactions of Ceftiofur Sodium with H2-Receptor Antagonist
Lovely Professional University, School of Chemical Engineering and Physical Sciences, Phagwara-144411, 1Department of Chemistry, IIS University, Jaipur, 2Department of Chemistry, University of Rajasthan, Jaipur, India
Lovely Professional University, School of Chemical Engineering and Physical Sciences, Phagwara-144411, E-mail: firstname.lastname@example.org
The purpose of this study was to examine the possible drug-drug interactions between ceftiofur sodium and famotidine on co-administration. These studies were carried out at normal as well as elevated temperature at pH corresponding to blood pH of 7.4. Spectrophotometric method was used to study the dissolution of each drug individually and in the presence of the other drug. Change in the rate of dissolution of ceftiofur sodium in the presence of cimetidine as compared to the rate of dissolution in the absence of cimetidine supported the possible interactions between the two drugs.