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Abstract

Interactions of Ceftiofur Sodium with H2-Receptor Antagonist

Author(s): N. Tandon*, Raakhi Gupta1 AND Neelima Gupta2
Lovely Professional University, School of Chemical Engineering and Physical Sciences, Phagwara-144411, 1Department of Chemistry, IIS University, Jaipur, 2Department of Chemistry, University of Rajasthan, Jaipur, India

Correspondence Address:
Lovely Professional University, School of Chemical Engineering and Physical Sciences, Phagwara-144411, E-mail: [email protected]


The purpose of this study was to examine the possible drug-drug interactions between ceftiofur sodium and famotidine on co-administration. These studies were carried out at normal as well as elevated temperature at pH corresponding to blood pH of 7.4. Spectrophotometric method was used to study the dissolution of each drug individually and in the presence of the other drug. Change in the rate of dissolution of ceftiofur sodium in the presence of cimetidine as compared to the rate of dissolution in the absence of cimetidine supported the possible interactions between the two drugs.

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