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Preliminary phytochemical screening and antimicrobial studies of Lantana indica roxb

Author(s): R Venkataswamy1, A Doss2, M Sukumar1, HM Mubarack2
1 Department of Pharmacognosy, SRIPMS College of Pharmacy, Coimbatore-641 044, India 2 Department of Microbiology, RVS College of Arts and Science, Sulur, Coimbatore-641 402, India

Correspondence Address:
R Venkataswamy Department of Pharmacognosy, SRIPMS College of Pharmacy, Coimbatore-641 044 India E-mail: [email protected]

The aim of the present study was to investigate the antimicrobial and preliminary phytochemical properties of Lantana indica Roxb. The aqueous and organic solvent (ethyl acetate and methanol) extracts from the leaves of Lantana indica (Verbenaceae) were tested against Staphylococcus aureus, Bacillus subtilis, Steptococcus pyrogens, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi, Aspergillus niger and Candida albicans by agar well diffusion method. The results showed promising antibacterial activity against the tested bacteria. Among these, methanol and aqueous extracts were found to possess a more potent inhibitory effect when compared to the ethyl acetate extract. Preliminary phytochemical analysis of extracts revealed the presence of antimicrobial compounds such as carbohydrates, proteins, tannins and flavonoidal glycosides. The result of this study validates the use of methanol and aqueous extract of this species in ethnomedicine, favouring the isolation of antibacterial agents from the leaf extract of Lantana indica.

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