Protective Efficacy of Two Endemic Strobilanthes of Southern Western Ghats, Kerala
Cell and Molecular Biology Division, Department of Botany, University of Calicut, Thenhipalam, Kerala 673635, India
Reshmi Chembrammal, Cell and Molecular Biology Division, Department of Botany, University of Calicut, Thenhipalam, Kerala 673635, India, E-mail: email@example.com
Modern food habits in humans have increased the frequency of diseases especially colon cancer. The present findings suggest the potential efficacy of two endemic Strobilanthes species of Southern Western Ghats. The shoot extract of the plants showed high radical scavenging activity in hydroxyl scavenging assay at an half maximal inhibitory concentration of 375.24±2.03 and 375.24±2.03 μg/ml against gallic acid for Strobilanthes anamallaica and Strobilanthes virendrakumarana respectively. Their activity in the superoxidefree radical assay was moderate when compared with the standard. Among the two species, Strobilanthes virendrakumarana highly impacted colon cancer cells (DLD1) with an Lethal concentration 50 of 111.99±4.91 μg/ml. These concentrations do not affect the normal cell line L929 under consideration. Hence, the endemic plant of Southern-Western Ghats, viz., Strobilanthes virendrakumarana is a promising candidate against colon cancer cells.