Risk Factors of Hypertension Disease during Pregnancy and their Influence on Pregnancy Outcome and Newborns
Department of Paediatric Intensive Care Unit, The Second School of Clinical Medicine, Lanzhou University, Gansu Provincial Maternity and Child-care Hospital Gansu 730030, 1Department of Endoscopy Center, 2Department of Paediatric Intensive Care Unit, 3Department of Scientific Research Center, 4Department of Perinatal Medical Center, Gansu Provincial Maternity and Child-care Hospital, Lanzhou, Gansu 730050, 5Department of Hypertension Center, Lanzhou University Second Hospital, Lanzhou, Gansu 730030, China
B. Yi, Department of Scientific Research Center, Gansu Provincial Maternity and Child-care Hospital, Lanzhou, Gansu 730050, China, E-mail: firstname.lastname@example.org
The high-risk factors of hypertension disease during pregnancy were retrospectively analyzed for their influence on pregnancy outcome and newborns. 72 patients with pregnancy hypertension admitted to the Department of Obstetrics and Gynecology in our hospital from December 2019 to December 2020 were retrospectively analyzed and set as the study group. At the same time, the 72 cases of healthy pregnancy subjects who received birth checkups during the same period were included as the control group. Self-made questionnaire was used to survey the basic information of the subjects, including age, income, emotions, living habits, education level and other related factors. Pregnancy outcome and neonatal complications were statistically measured and then univariate and multivariate logistic analysis methods were adopted to investigate their main risk factors. Univariate analysis found that 7 factors including age, body mass index, monthly income, education level, family history of hypertension, pregnancy complications and negative emotions are related to the onset of hypertension disease in pregnancy, and further multivariate unconditional logistic regression analysis showed that body mass index, education level, family history of hypertension and negative emotions are risk factors for the onset of hypertension disease in pregnancy; the incidence of fetal distress, low birth weight infants, perinatal death and neonatal asphyxia in the study group were significantly higher than that in the control group, the difference was statistically significant (p<0.05). In the study group, there were 17 cases of serious complications and 11 cases of more than two complications and in the control group, there were 8 cases of serious complications and 4 cases of more than two complications. The difference was statistically significant after testing (p<0.05). Obesity during pregnancy, low education level, family history of hypertension and negative emotions are risk factors for hypertension disease during pregnancy. In addition, hypertension disease during pregnancy can adversely affect pregnancy outcome and newborns, and clinical prevention and health care should be strengthened.