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Abstract
Spectrophotometric estimation of Gatifloxacin in tablets
Author(s): AV Mali, RP Dhavale, VL Mohite, AR Mahindrakar, YV Pore, BS Kuchekar
Government College of Pharmacy, Vidyanagar, Karad-415 124, India
Correspondence Address:
B S Kuchekar Government College of Pharmacy, Vidyanagar, Karad-415 124 India E-mail: bskuchekar2000@yahoo.com
Government College of Pharmacy, Vidyanagar, Karad-415 124, India
Correspondence Address:
B S Kuchekar Government College of Pharmacy, Vidyanagar, Karad-415 124 India E-mail: bskuchekar2000@yahoo.com
A simple, sensitive, rapid, accurate, and precise spectrophotometric method has been developed for estimation of gatifloxacin in pharmaceutical dosage forms. The method is based on formation of orange coloured chromogen due to reaction of gatifloxacin with ferric nitrate reagent solution, which exhibits maximum absorption at 470 nm against blank. Stability of chromogen was found up to 1 h, and chromogen obeyed linearity over 20-200 µg/ml.
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