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Abstract

Spectrophotometric estimation of olmesartan medoxomil and hydrochlorothiazide in tablet

Author(s): AR Rote, PD Bari
Department of Pharmaceutical Chemistry, MGV's Pharmacy College, Panchavati, Mumbai Agra Road, Nashik-422 003, India E-mail: [email protected]

Correspondence Address:
A R Rote Department of Pharmaceutical Chemistry, MGV's Pharmacy College, Panchavati, Mumbai Agra Road, Nashik-422 003 India


A simultaneous determination of olmesartan medoxomil and hydrochlorothiazide by absorption ratio spectrophotometric method has been developed in combined tablet dosage form. The method is based on measurements of absorbance at isoabsoptive point. The Beer's law obeys in the range of 10-30 mg/ml for both olmesartan medoxomil and hydrochlorothiazide respectively. The proposed method was validated by performing recovery study and statistically.

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