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Abstract

Spectroscopic and electrochemical analysis of psychotropic drugs

Author(s): H Puzanowska-Tarasiewicz, W Misiuk, K Mielech-Lukasiewicz, L Kuzmicka
Institute of Chemistry, University of Bialystok, Hurtowa 1, Bialystok 15-399, Poland

Correspondence Address:
L Kuzmicka Institute of Chemistry, University of Bialystok, Hurtowa 1, Bialystok 15-399 Poland [email protected]


Psychotropic drugs are an important family of compounds from a medical point of view. Their application in therapy requires methods for the determination in pharmaceutical dosage forms and body fluids. Several methods for their analysis have been reported in the literature. Among the methods, spectrophotometric and electrochemical are very useful for the determination of the drugs. Some of the spectrophotometric methods are based on the formation of the binary and ternary compounds with complexes of metals. The formed compounds are sparingly soluble in water, but quantitatively extracted from aqueous phase into organic solvents and the extracts are intensely colored and stable for a few days. These complexes have been employed in pharmaceutical analysis. The electrochemical procedures are very useful in determination of the psychotropic substances in pharmaceutical preparations.

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