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Abstract

Synthesis and pharmacological screening of 5-methyl-3-[ P -(6'-aryl-2'-thioxo-1',2',5',6'-tetrahydro-pyrimidin-4'-yl)-phenyl]-3 H -2-oxo-D4-1,3,4-oxadiazoles

Author(s): RR Kamble, BS Sudha
Department of Studies in Chemistry, Yuvaraja's College, University of Mysore, Mysore-570 005, India

Correspondence Address:
R R Kamble Department of Studies in Chemistry, Yuvaraja's College, University of Mysore, Mysore-570 005 India E-mail: ravichem1234@rediffmail.com


The title compounds were synthesised by using cyclization of a, b-unsaturated ketones and thiourea, in presence of a base. All the newly synthesised compounds have been characterised by elemental analyses, spectral data, and screened for antibacterial, antifungal, anti-inflammatory, and anticonvulsant activities.

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Citations : 66710

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