Abstract
Validated HPTLC method for simultaneous determination of quinapril hydrochloride and hydrochlorothiazide in a tablet dosage form
Author(s): Girija B Bhavar2, VA Chatpalliwar2, DD Pati2, SJ Surana2
2Department of Pharmaceutical Chemistry, R. C. Patel College of Pharmacy Karvand Naka, Shirpur, Dist: Dhule-425 405, India 2 Department of Pharmaceutical Chemistry, H. R. Patel College of Pharmacy Karvand Naka, Shirpur, Dist: Dhule-425 405, India
Correspondence Address:
V A Chatpalliwar Department of Pharmaceutical Chemistry, R. C. Patel College of Pharmacy Karvand Naka, Shirpur, Dist: Dhule-425 405 India E-mail: vchatpalliwar@yahoo.co.in
2Department of Pharmaceutical Chemistry, R. C. Patel College of Pharmacy Karvand Naka, Shirpur, Dist: Dhule-425 405, India 2 Department of Pharmaceutical Chemistry, H. R. Patel College of Pharmacy Karvand Naka, Shirpur, Dist: Dhule-425 405, India
Correspondence Address:
V A Chatpalliwar Department of Pharmaceutical Chemistry, R. C. Patel College of Pharmacy Karvand Naka, Shirpur, Dist: Dhule-425 405 India E-mail: vchatpalliwar@yahoo.co.in
Quinapril hydrochloride and hydrochlorothiazide were simultaneously determined by HPTLC in pharmaceutical formulations. The drugs were separated on silica gel 60 F 254 plates using suitable combination of solvents as mobile phase. The validation parameters, tested in accordance with the requirements of ICH guidelines, prove the suitability of methods.
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