Review Article p. 849

Rethinking Chronic Pain Treatment with Opioids

Nikunja B. Pati*, V. R. M. Gupta, V. Mayasa, Swapna Velivela and MD. Ashwaq Hussain

Opioid analgesics are defined as drugs that stimulate opioid receptors, primarily used in the treatment of moderate to severe pain. Since the discovery of opioids, they are considered as the..

Review Article p. 858

Pharmaceutical Cocrystals: An Overview

S. Kumar and A. Nanda*

Poor aqueous solubility and low oral bioavailability of an active pharmaceutical ingredient are the major constraints during the development of new product. Various approaches have been used..

Research Paper p. 872

In vitro Evaluation of Antioxidant and Antiproliferative Activities of Artemisia nilagirica Extracts

M. Z. Gul, M. Y. Bhat, R. Maurya, I. A. Qureshi, and I. A. Ghazi*

Medicinal plants serve as unlimited source for phytoconstituents that possess potent antioxidant and antiproliferative properties. Artemisia nilagirica L. is a potent medicinal plant widely ..

Research Paper p. 885

High-Performance Liquid Chromatography Determination of Praziquantel in Rat Plasma; Application to Pharmacokinetic Studies

S. Dey, M. Ghosh, N. K. Rangra*, K. Kant, S. R. Shah, P. K. Pradhan and S. Singh

A very simplistic, selective, sensitive, and reproducible procedure based on a reversed-phase high-performance liquid chromatography was used and developed for the determination of praziquan..

Research Paper p. 893

Synthesis, DNA-Binding and Antibacterial Activity of the Cell-Penetrating Peptide HIV-1 Tat (49-57)

Ming Xiu. Lv, B. C. Duan, K. Lu*, Y. J. Wu and Y. F. Zhao*

The interaction of cell-penetrating peptide human immunodeficiency virus transacting activator of transcription, peptide Tat (49–57), which is the minimal transduction domain of human ..

Research Paper p. 900

Different Antioxidant Activity Measurements of the Aerial Parts of Ferulago angulate, Traditional Food Additives in Iran

E. Golezar, H. Mahdiuni* and A. Nazari

In this study ferric reducing antioxidant power assay, 2,2-diphenyl-1-picrylhydrazyl and oxygen radical absorbance capacity assays were employed to measure the antioxidant activity of flower..

Research Paper p. 907

Design of the Lyophilization Process of a Doxorubicin Formulation Based on Thermal Properties

A. A. Hajare* and H. N. More

The frontline chemotherapy used for treatment of several forms of cancer is doxorubicin, which is required to be lyophilized due to its limited storage stability. Results from differential t..

Research Paper p. 914

Formulation Optimization, Rheological Characterization and Suitability Studies of Polyglucoside-based Azadirachta indica A. Juss Emollient Cream as a Dermal Base for Sun Protection Application

Kaushita Banerjee, N. Thiagarajan and Padma Thiagarajan*

Polyglucoside emulsifiers have been very beneficial for blending natural oils with water for formulation of emollient creams that can serve as effective topical applicants. In the present st..