Review Article p. 581

Pathogenesis of Alzheimer's Disease: Role of Amyloid-beta and Hyperphosphorylated Tau Protein

Rabia Sajjad, Rawaba Arif, A. A. Shah, I. Manzoor and G. Mustafa*

The pathological emblems of Alzheimer’s disease are the accumulation of amyloid-β plaques and neurofibrillary tangles. The alluvium of toxic amyloid-β-protein in the form of ..

Review Article p. 592

Advances in Biogenic Nanoparticles and the Mechanisms of antimicrobial Effects

Afifa Qidwai, A. Pandey, R. Kumar, S. K. Shukla and A. Dikshit*

Innovations in the nanotechnological arena have paved a path leading to nano-revolution, which has most recently unfurled the role of plants in the biogenic synthesis of nanoparticles. Thoug..

Research Paper p. 604

Development of Colon-targeted Microsponges for the Treatment of Inflammatory Bowel Disease

S. Janakidevi* and K. V. Ramanamurthy

The present study is aimed to develop and characterize microsponge-based novel colon-specific drug delivery systems containing 5-amino salicylic acid for the treatment of inflammatory bowel ..

Research Paper p. 610

Drug Utilization Pattern of Ciprofloxacin, Meropenem and Amikacin in Tertiary Care Hospital in Pakistan

H. Ali, S. Alam , F. Zafar , R. Bushra, S. Saleem, F. Israr, G. R. Naqvi, N. Mallick, A. Tariq and R. Fatima

Drug utilization pattern is premeditated to evaluate appropriateness of drug usage. The current study was performed in a multifaceted tertiary care setting in qualitative and cross sectional..

Research Paper p. 619

Synthesis, Characterization, Antimicrobial and Density Functional Theory Studies of Metal Complexes of 3-Benzoyl-7-methoxy Coumarin

S. Radha, K. K Mothilal*, A .Thamaraichelvan and R. Shanmugam

A series of three metal complexes of the 3-benzoyl-7-methoxycoumarin ligand have been synthesized and characterized by elemental analyses, molar conductance, Fourier-transform infrared spect..

Research Paper p. 628

Optimized Gas Chromatography-Mass Spectrometric Method to Profile Esterified Fatty Acids in Fish Roe and Fish Oil

Alaa Khedr* and A. M. Alahdal

A gas chromatography-mass spectrometric method was optimized and applied to profile the major esterified fatty acids in eight lyophilized fish roe species and three marketed fish oil capsule..

Research Paper p. 637

Antinociceptive and Antiinflammatory Activities of Anastatica hierochuntica and Possible Mechanism of Action

A. Alatshan, Esam Qnais, M. Wedyan, Y. Bseiso, Elham Alzyoud, Rihan Banat and H. Alkhateeb

Anastatica hierochuntica L. (Brassicaceae) has been used in folk medicine to treat diseases related to inflammation and pain. This study investigated the antinociceptive and antiinflammatory..

Research Paper p. 647

Ultrasound-induced Microencapsulation of Simvastatin for Gastro Retention and Controlled Delivery

H. S. Shekar, A. J. Rajamma* and S. B. Sateesha

The objective of this study is to demonstrate an effective technique with potential for commercialization for microsphere production. Ultrasound-assisted ionic gelation of sodium alginate wa..