Abstract

Diabetes, a chronic disease metabolic disorder, commonly affects people. Human lifestyle is changing with the rapid development of the global economy. The incidence of diabetes mellitus is increasing year by year and is becoming more prevalent with rapid global economic development, changing lifestyles and aging problems. We retrieved the data of random controlled trials from 8 databases based on the influences of aerobic exercise on cognitive function in patients with type 2 diabetes mellitus. We utilized review manager 5.3 software to analyze the data after evaluating the literature. We selected 10 random controlled trials to perform this comprehensive meta-analysis. We found that 10 studies derived the information of cognitive function between the test and the control groups and the cognitive function is significantly higher in the test group (standardized mean differences: 1.88; 95 % confidence interval: 0.91, 2.84; p<0.01) than the control group. Moreover, the test group showed significantly higher mini-mental state examination (standardized mean differences: 2.06; 95 % confidence interval: 0.96, 3.14; p<0.01) and Montreal cognitive assessment (standardized mean differences: 1.62; 95 % confidence interval: 0.54, 2.69; p<0.01) than the normal group. Our findings demonstrated that aerobic exercise is crucially potent in type 2 diabetes mellitus patients and cognitive impairment, as evidenced by total cognitive function, mini-mental state examination and Montreal cognitive assessment. The above results should be warranted to verify with sophisticated clinical trials.