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Review Article p. 928

Bioactives Profile of Purple and Black Tomato: Potential Applications in the Pharmaceutical Field Purple and Black Tomato

SIMONE PERNA, SHERRY NASRALLA TAWFIK, T.ARIQ A. ALALWAN, CLARA GASPARRI, GABRIELLA PERONI, ZAHRAA ALAALI, HIND MUBARAK, EBTISAM BIN BUTTI, MONA A. AZIZ ALJAR, VITTORIA INFANTINO, MARIANGELA RONDANELLI

The purple and black tomato are sources of different antioxidants such as carotenoids and flavonoids that seem to have dose-dependent antioxidant, anti-inflammatory, anti-proliferative and..

Review Article p. 936

Handling of Pharmaceutical Deviations: A Detailed Case Study

DAMINI V, S. H. KUMAR*, H. V. GANGADHARAPPA AND M. P. GOWRAV

Deviations are the differences which are measured between the expected or normal values and the observed values for a product or process condition from a procedure or a documented standar..

Review Article p. 945

Traditional and Advanced Flow Characterization Techniques: A Platform Review for Development of Solid Dosage Form

K. K. MORAVKAR, S. D. KORDE, B. A. BHAIRAV, S. B. SHINDE, S. V. KAKULADE AND S. S. CHALIKWAR*

Preformulation studies like storage, transfer, fluidisation, and compaction, are subject to the excellent flowability of the powder. It is often required for proper operational managem..

Research Article p. 958

Development and Validation of Novel and Highly Sensitive Stability-Indicating Reverse Phase Ultra Performance Liquid Chromatography Method for Quantification of Ibrutinib and its ten Degradation Products

L. MEHTA,*, T. NAVED, P. GROVER, M. BHARDWAJ, AND D. MUKHERJEE

In present study, a novel, simple, robust, stability-indicating, highly sensitive and specific reverse phase ultra-performance liquid chromatographic method was established and validated ..

Research Article p. 967

Cytotoxic and Apoptotic Efficacy of Concanavalins Isolated from Canavalia ensiformis and Canavalia gladiata on Colon Carcinoma Cells

GEETHA SUVARNA, ASHWINI PRABHU, KATHEEJA MUHSEENA N AND BHAGYA B. SHARMA*

Concanavalin a lectin from seeds of Canavalia spp. is extracted and purified to study antitumor effect in vitro. Canavalia ensiformis and Canavalia gladiata were tested for their cytotoxi..

Research Article p. 974

Development of Novel Crystal Forms of Metaxalone for Solubility Enhancement

M. S. AZIZ, CHITRA GUPTA AND L. K. TYAGI*

Metaxalone is oxazolidin-2-one derivative, biopharmaceutics classification system class II drug, available in the market as a central muscle relaxant drug, used to alleviate discomforts a..

Research Article p. 996

A Comprehensive Study of the Neuropharmacological Profile of Methanol Leaf Extract of Aloe vera and Identification of Associated Neuroprotective Compounds through Gas chromatography-mass spectrometry Analysis

MEERA RATH, AYON BHATTACHARYA*, KARMAJEET RATH, SOUMYA SANTRA, GOUTAM GHOSH AND BIJAYA B NANDA

The objective of this study is to determine the neuropharmacological activities of the methanol extract of Aloe vera leaf and identify the potential bioactive compounds present in the sam..

Research Article p. 984

Synthesis, Characterization and Docking Studies of N-Methyl-2, 3-Dihydro Quinazolin-4-Ones Linked 1,3-Thiazole Hybrids as Potent Anti-Tubercular Agents

N. NAGALADINNE*, A. A. HINDUSTAN AND D. NAYAKANTI

Quinazolin-4-ones connected 1, 3-thiazole were found with antibacterial action after high throughput screening. N-Methyl Anthranilic acid when treated with thiophene-2-carboxylic acid giv..